News | Veprintsev Lab

PhD position: Machine Learning guided design of GPCR ligands with desired pharmacology.

Adrenoceptors are G protein coupled receptors that mediate the action of adrenalin on heart rate or dilation of airways. The project will...

“Prediction of ligand-receptor pharmacological activities using a combined docking and machine learning approach” by Mireia Jimenez-Roses...

Our latest BioRxiv preprint describing a set of 35 cannabinoid ligands with full ADME properties dialling the signalling bias in a...

Edward and Akhil will focus on genetic basis for GPCR-related diseases.

Happy to share our latest ThermoBRET method to measure protein stability in unpurified samples. It is based on BRET between a novel...

https://www.biorxiv.org/content/10.1101/2020.07.07.191957v1 Congratulations David Tippett - our star summer student - with his first...

Zoe and Rohini are joining the Veprintsev lab this summer to complete their master research projects as part of the Drug discovery and...

https://www.biorxiv.org/content/10.1101/2020.06.29.171512v1

Congratulations to Leire Borrega on being awarded an EMBO short term fellowship to help support her work in the Veprintsev lab....

Our protocol for high-throughput site directed scanning mutagenesis using our two fragment PCR approach, alanine scanning software and...

As part of the BBSRC MIBPT program Dr C Gorvin and Professor D Veprintsev are are advertising a PhD position 'Understanding how GPCRs...

Our two papers describing the development of fluorescent CB2 ligands are published on ChemRxiv. Congratulations to all collaborators!...

Asuman Bunsuz joins the lab to study the molecular basis of efficacy of GPCR pharmacological ligands by combining computational and...

He will study the molecular basis of allosteric modulation.